Üç eyler Lab

People

Prof. Dr. Nurcan Üçeyler

Department of Neurology, University Hospital of Würzburg

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Publications (selected list)

Ullrich M, Weber M, Post AM, Popp S, Grein J, Zechner M, Guerrero González H, Kreis A, Schmitt AG, Üçeyler N, Lesch KP, Schuh K (2017). OCD‐like behavior is caused by dysfunction of thalamo‐amygdala circuits and upregulated TrkB/ERK‐MAPK signaling as a result of SPRED2 deficiency. Mol Psychiatry doi:10.1038/mp.2016.232.


Attal N, de Andrade DC, Adam F, Ranoux D, Teixeira MJ, Galhardoni R, Raicher I, Üçeyler N, Sommer C, Bouhassira D (2016). Safety and efficacy of repeated injections of botulinum toxin A in peripheral neuropathic pain (BOTNEP): a randomised, double-blind, placebocontrolled trial. Lancet Neurol 15:555–565.


Leinders M, Doppler K, Klein T, Deckart M, Rittner H, Sommer C, Üçeyler N (2016). Increased cutaneous miR-let-7d expression correlates with small nerve fiber pathology in patients with fibromyalgia syndrome. Pain 157:2493–2503.


Lemmer S, Schießer P, Geis C, Sommer C, Vanegas H, Üçeyler N (2015). Enhanced spinal neuronal responses as a mechanism for the increased nociceptive sensitivity of interleukin-4 deficient mice. Exp Neurol 271:198–204.


Üçeyler N, Zeller D, Kahn AK, Kewenig S, Kittel-Schneider S, Schmid A, Casanova-Molla J, Reiners K, Sommer C (2013). Small fibre pathology in fibromyalgia syndrome. Brain 136:1857–1867.


Üçeyler N, Devigili G, Toyka KV, Sommer C (2010). Skin biopsy as an additional diagnostic tool in non-systemic vasculitic neuropathy. Acta Neuropathol 120:109–116.


Üçeyler N, Kafke W, Riediger N, He L, Necula G, Toyka KV, Sommer C (2010). Elevated proinflammatory cytokine expression in affected skin in small fiber neuropathy. Neurology 74:1806–1813.


Häuser W, Bernardy K, Üçeyler N, Sommer C (2009). Treatment of fibromyalgia syndrome with antidepressants: a meta-analysis. JAMA 301:198–209.


Üçeyler N, Rogausch JP, Toyka KV, Sommer C (2007). Differential expression of cytokines in painful and painless neuropathies. Neurology 69:42–49.


Üçeyler N, Valenza R, Stock M, Schedel R, Sprotte G, Sommer C (2006). Reduced levels of antiinflammatory cytokines in patients with chronic widespread pain. Arthritis Rheum 54:2656–2664.

Research

Corneal confocal microscopy of a control subject (A) with high nerve fiber density and a chronic pain patient with reduced corneal innervation (B).

microRNA expression analysis in blood samples of patients with painful versus painless conditions.

Assessment of mechanical sensitivity with the von Frey test in rodents.

Corneal confocal microscopy of a control subject (A) with high nerve fiber density and a chronic pain patient with reduced corneal innervation (B).