Previous publications

December 2018

Kasaragod VB, Hausrat TJ, Schaefer N, Kuhn M, Christensen NR, Tessmer I, Maric HM, Madsen KL, Sotriffer C, Villmann C, Kneussel M, Schindelin H (2018) Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins Neuron 20;101(4):673-689.e11 DOI: 10.1016/j.neuron.2019.01.001

Hofmann L, Hose D, Griesshammer A, Blum R, Doring F, Dib-Hajj S, Waxman S, Sommer C, Wischeyer E, Uceyler N (2018) Characterization of small fiber pathology in a mouse model of Fabry disease. Elife 7(e39300).  DOI: 10.7554/eLife.39300.001

Martin C, Stoffer C, Mohammadi M, Hugo J, Leipold E, Oehler B, Rittner HL, Blum R (2018) NaV1.9 Potentiates Oxidized Phospholipid-Induced TRP Responses Only under Inflammatory Conditions. Front Mol Neurosci 11(7):7. DOI: 10.3389/fnmol.2018.00007

Mohammadi M, Oehler B, Kloka J, Martin C, Brack A, Blum R, Rittner HL (2018) Antinociception by the anti-oxidized phospholipid antibody E06. Br J Pharmacol 175(14):2940-55. DOI: 10.1111/bph.14340

Prada J, Sasi M, Martin C, Jablonka S, Dandekar T, Blum R (2018). An open source tool for automatic spatiotemporal assessment of calcium transients and local 'signal-close-to-noise' activity in calcium imaging data. PLoS Comput Biol 14(3):e1006054. DOI: 10.1371/journal.pcbi.1006054

October 2018

Hein G, Engelmann JB, Tobler PN (2018) Pain relief provided by an outgroup member enhances analgesia Proc Roy Soc Biol 285(1887). DOI: 10.1098/rspb.2018.0501

September 2018

Breitinger U, Bahnassawy LM, Janzen D, Roemer V, Becker CM, Villmann C, Breitinger HG (2018) PKA and PKC modulators affect ion channel function and internalization of recombinant alpha1 and alpha1 beta glycine receptors. Front Mol Neurosci 11:154. DOI: 10.3389/fnmol.2018.00154


Fadok JP, Markovic M, Tovote P, Lüthi A (2018) New perspectives on central amygdala function. Curr Opin Neurobiol 49:141-147. DOI: 10.1016/j.conb.2018.02.009


Milanos S, Kuenzel K, Gilbert DF, Janzen D, Sasi M, Buettner A, Frimurer TM, Villmann C (2018) Structural changes at the myrtenol backbone reverse its positive allosteric potential into inhibitory GABAA receptor modulation. Biol Chem 399(6):549-563. DOI: 10.1515/hsz-2017-0262


Schaefer N, Roemer V, Janzen D, Villmann C (2018) Impaired glycine receptor trafficking in neurological diseases. Front Mol Neurosci. 2018 11:291. DOI: 10.3389/fnmol.2018.00291


Schaefer N, Zheng F, van Brederode J, Berger A, Leacock S, Hirata H, Paige CJ, Harvey RJ, Alzheimer C, Villmann C. (2018) Functional consequences of the postnatal switch from neonatal to mutant adult glycine receptor alpha1 subunits in the shaky mouse model of startle disease. Front Mol Neurosci 11:167. DOI: 10.3389/fnmol.2018.00167

July 2018

Beck K, Hovhanyan A, Menegazzi P, Helfrich-Förster C, Raabe T (2018) Drosophila RSK sets the pace of the circadian clock by negative regulation of protein kinase Shaggy. Front Mol Neurosci 11:122. DOI: 10.3389/fnmol.2018.00122


Beer K, Kolbe E, Kahana N, Yayon N, Weiss R, Menegazzi P, Bloch G, Helfrich-Förster C (2018) Pigment-Dispersing Factor expressing neurons provide an infrastructure for conveying circadian information in the honey bee brain. Open Biology 8, 170224. DOI: 10.1098/rsob.170224 

Bertolini E, Kistenpfennig C, Menegazzi P, Koukidou M, Helfrich-Förster C (2018) The characterization of the circadian clock in the olive fly Bactrocera oleae (Diptera: Tephritidae) reveals a Drosophila-like organization. Sci Reports 8, 816. DOI: 10.1038/s41598-018-19255-8 

Helfrich-Förster C (2018) Sleep in insects. Annu Rev Entomol 63, 69-86. DOI: 10.1146/annurev-ento-020117-043201 


Kay J, Menegazzi P, Mildner S, Roces F, Helfrich-Förster C (2018) The circadian clock of the ant Camponotos floridanus is localized in dorsal and lateral neurons of the brain. J Biol Rhythms 33(3):255-271.  DOI: 10.1177/0748730418764738 

Kistenpfennig C, Nakayama M, Nihara R, Tomioka K, Helfrich-Förster C, Yoshii T (2018) A tug-of-war between Cryptochrome and the visual system allows the adaptation of evening activity in long summer days in Drosophila melanogaster. J Biol Rhythms 33, 24-34. DOI: 10.1177/0748730417738612


Pilorz V, Helfrich-Förster C, Oster H (2018) The role of the circadian clock system in physiology. Pflügers Arch, doi: 10.1007/s00424-017-2103-y. DOI: 10.1007/s00424-017-2103-y 


Schlichting M, Rieger D, Cusumano P, Grebler R, Costa R, Mazotta GM, Helfrich-Förster C (2018) Cryptochrome interacts with actin and enhances eye-mediated light sensitivity of the circadian clock in Drosophila melanogaster. Front Mol Neurosci 11:238 DOI: 10.3389/fnmol.2018.00238  


Schubert FK, Hagedorn N, Yoshii T, Helfrich-Förster C, Rieger D (2018) Neuroanatomical details of the lateral neurons of Drosophila melanogaster support their functional role in the circadian system. J Comp Neurol 526(7):1209-1231. DOI: 

June 2018

Yuan X, Klein D, Kerscher S, West BL, Weis J, Katona I, Martini R (2018) Macrophage Depletion Ameliorates Peripheral Neuropathy in Aging Mice. J Neurosci 9;38(19):4610-4620. DOI: 10.1523/JNEUROSCI.3030-17.2018

March 2018

Prada J, Sasi M, Martin C, Jablonka S, Dandekar T, Blum R (2018) An open source tool for automatic spatiotemporal assessment of calcium transients and local 'signal-close-to-noise' activity in calcium imaging data. PLoS computational biology 14:e1006054 DOI: 10.1371/journal.pcbi.1006054  The computer tool is available through:

​Pfeiffer V, Götz R, Camarero G, Heinsen H, Blum R, Rapp UR (2018) Impaired neuronal maturation of hippocampal neural progenitor cells in mice lacking CRAF. PloS One 13:e0192067 DOI: 10.1371/journal.pone.0192067

Selcho M, Mühlbauer B, Hensgen R, Shiga S, Wegener C, Yasuyama K. (2018) Anatomical characterization of PDF‐tri neurons and peptidergic neurons associated with eclosion behavior in Drosophila. J Comp Neurology 526, Nr. 8: 1307–28. DOI: 10.1002/cne.24408.

Wendt JHamm AOPané-Farré CAThayer JFGerlach AGloster ATLang T, Helbig-Lang SPauli PFydrich TStröhle AKircher TArolt VDeckert JWittchen HU,Richter J (2018) Pretreatment Cardiac Vagal Tone Predicts Dropout from and Residual Symptoms after Exposure Therapy in Patients with Panic Disorder and Agoraphobia. Psychother Psychosom, DOI: 10.1159/000487599

February 2018

Martin C, Stoffer C, Mohammadi M, Hugo J, Leipold E, Oehler B, Rittner HL, Blum R (2018) NaV1.9 Potentiates Oxidized Phospholipid-Induced TRP Responses Only under Inflammatory Conditions. Front Mol Neurosci, 11, 1-7. DOI: 10.3389/fnmol.2018.00007W

January 2018

Genheimer H, Andreatta M, Asan E, Pauli P (2018) Reinstatement of contextual conditioned anxiety in virtual reality and the effects of transcutaneous vagus nerve stimulation in humans. Sci Rep, 7(1):17886. DOI: 10.1038/s41598-017-18183-3 

Reinhard P, Neupert S, Derst C, Reinhardt, K, Wegener, C. (2018) Neuropeptidomics of the Bed Bug Cimex Lectularius J Prot Research 17, 1: 440–54. DOI: 10.1021/acs.jproteome.7b00630

November 2017

Beer K, Joschinski J, Arrazola Sastre A, Krauss J, Helfrich-Förster C (2017). A damping circadian clock drives weak oscillations in metabolism and locomotor activity of aphids (Acyrthosiphon pisum). Scientific Reports, 2;7(1):14906. doi:10.1038/s41598-017-15014-3.

Berti S, Vossel G, Gamer M (2017) The orienting response in healthy aging: novelty P3 indicates no general decline but reduced efficacy for fast stimulation rates. Frontiers in Psychology, 8, 1780. doi:10.3389/fpsyg.2017.01780


Fluri F, Malzahn U, Homola GA, Schuhmann MK, Kleinschnitz C, Volkmann J (2017). Stimulation of the mesencephalic locomotor region for gait recovery after stroke. Annals of Neurology, 82(5):828-840. doi: 10.1002/ana.25086.


Janzen D, Schaefer N, Delto C, Schindelin H, Villmann C. (2017) The GlyR extracellular b8-b9 loop – a functional determinant of agonist potency. Front Mol Neurosci. 2017 Oct 9;10:322. doi: 10.3389/fnmol.2017.00322. eCollection 2017.


Lischke A, Herpertz S C, Berger C, Domes G, Gamer M (2017) Divergent effects of oxytocin on (para-)limbic reactivity to emotional and neutral scenes in females with and without borderline personality disorder. Social, Cognitive and Affective Neuroscience. doi: 10.1093/scan/nsx107


Lüningschrör P, Binotti B, Dombert B, Heimann P, Perez-Lara A, Slotta C, Thau-Habermann N, R von Collenberg C, Karl F, Damme M, Horowitz A, Maystadt I, Füchtbauer A, Füchtbauer EM, Jablonka S, Blum R, Üçeyler N, Petri S, Kaltschmidt B, Jahn R, Kaltschmidt C, Sendtner M (2017) Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease. Nature Communications 30, 8(1): 678. doi: 10.1038/s41467-017-00689-z.

Schmidt K, Gamer M, Forkmann K, Bingel U (2017) Pain affects visual orientation: an eye-tracking study. Journal of Pain. doi:10.1016/j.jpain.2017.09.005

October 2017

Dombert B, Balk S, Lüningschrör P, Moradi M, Sivadasan R, Saal-Bauernschubert L, Jablonka S (2017) BDNF/trkB Induction of Calcium Transients through Cav2.2 Calcium Channels in Motoneurons Corresponds to F-actin Assembly and Growth Cone Formation on β2-Chain Laminin (221). Frontiers in Molecular Neuroscience 10: 346.

Schaefer N, Berger A, van Brederode J, Zheng F, Zhang Y, Leacock S, Littau L, Jablonka S, Malhotra S, Topf M, Winter F, Davydova D, Lynch JW, Paige CJ, Alzheimer C, Harvey RJ, Villmann C. (2017) Disruption of a Structurally Important Extracellular Element in the Glycine Receptor Leads to Decreased Synaptic Integration and Signaling Resulting in Severe Startle Disease. J Neurosci. 2017 Aug 16;37(33):7948-7961.

Schaefer N, Rotermund C, Blumrich EM, Lourenco MV, Joshi P, Hegemann RU, Jamwal S, Ali N, García Romero EM, Sharma S, Ghosh S, Sinha JK, Loke H, Jain V, Lepeta K, Salamian A, Sharma M, Golpich M, Nawrotek K, Paidi RK, Shahidzadeh SM, Piermartiri T, Amini E, Pastor V, Wilson Y, Adeniyi PA, Datusalia AK, Vafadari B, Saini V, Suárez-Pozos E, Kushwah N, Fontanet P, Turner AJ. The malleable brain: plasticity of neural circuits and behavior - a review from students to students. J Neurochem. 2017 Jun 20. doi: 10.1111/jnc.14107. [Epub ahead of print] Review. PubMed PMID: 28632905.

September 2017

Forero A, Rivero O, Wäldchen S, Ku HP, Kiser DP, Gärtner Y, Pennington LS, Waider J, Gaspar P, Jansch C, Edenhofer F, Resink TJ, Blum R, Sauer M, Lesch KP (2017) Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain. Frontiers in Cellular Neuroscience 11: 307,

August 2017

Kistenpfennig C, Grebler R, Ogueta M, Hermann-Luibl C, Schlichting M, Stanewsky R, Senthilan PR, Helfrich-Förster C (2017) A new Rhodopsin influences light-dependent daily activity patterns of fruit flies. J Biol Rhythms 32, 406-422. DOI: 10.1177/0748730417721826

Scholz, N, Guan C, Nieberler M, Grotemeyer A, Maiellaro I, Gao S, Beck S, Pawlak M, Sauer M, Asan E, Rothemund S, Winkler J, Prömel S, Nagel G, Langenhan T, Kittel RJ (2017) Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons. eLife 6:e28360. Press release (German)

Oehler B, Kistner K, Martin C, Schiller J, Mayer R, Mohammadi M, Sauer RS, Filipovic MR, Nieto FR, Kloka J, Pflucke D, Hill K, Schaefer M, Malcangio M, Reeh PW, Brack A, Blum R, Rittner HL (2017) Inflammatory pain control by blocking oxidized phospholipid-mediated TRP channel activation. Scientific reports 7: 5447, doi:10.1038/s41598-017-05348-3

June 2017

Milanos S, Elsharif SA, Janzen D, Buettner A, Villmann C. Metabolic products of linalool and modulation of GABAA receptors. Front Chem. 2017 Jun 21;5:46. doi: 10.3389/fchem.2017.00046. eCollection 2017.


May 2017

Langlhofer G, Villmann C. The role of charged residues in independent glycine receptor folding domains for intermolecular interactions and ion channel function. J Neurochem. 2017 Jul;142(1):41-55. doi: 10.1111/jnc.14049. Epub 2017 May 22.

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